A 84 years old lady was unwell for a week and upon contact with the health services she was found to have a hemoglobin of 3.6 g%. To the left is her blood picture.
5-min Short Presentation
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Each presenter is allocated 5 minutes to talk about any topic related to haematology. Each person takes turn to particpate on a daily basis. Words that we say represents ideas that we wish to convey. Sometimes we say the things we intend to convey sometimes we don't. This exercise will allow each presenter to reflect and learn from his/her own presentation. Each presentation is associated with a comment area which is open to all to post. Perhaps this approach will induce discussion and enriched both the presenter and visitors. At the moment we expect the comment area to be regulated by the posters own maturity and sensibility. *Disclaimer: The information presented either through the video or comments is for learning/training purposes and there is no guarantee of its accuracy and should not be used for medical decision making without direct involvement of a qualified medical caregiver. Site moderated by Dr Abu Dzarr Abdullah. |
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The intro is OK. But the following point I will touch before moving on to describe the classical triad of multiple myeloma is to classify myeloma. Myeloma can be divided into symptomatic and asymptomatic/smoldering myeloma. Each of this category has its own diagnostic criteria, i.e percentage of plasma cell. Next I will not confine myself to bone lesion only when mentioning the triad but rather say that symptomatic myeloma involved abnormal deposit of clonal plasma cell proliferation producing paraprotein and myeloma related organ or tisu injury (ROTI). In asymptomatic myeloma obviously we will not expect ROTI to be present. It is not that only bone is affected as alluded in this talk. Rather there are couple of ROTI which can be involved. CRAB is the famous pseudoname for ROTI. Hypercalcaemia, renal failure, anaemia and bone lesion. When approaching treatment in myeloma towards the end, I will normally separate the discussion of treatment for young and elderly myeloma. Young is usually below 65 years old and is addressed with autoSCT in mind whereas in the elderly above 65 without autoSCT as the first line of treatment. The cut off point for elderly may differ from center to center.
30.06.10 13:50
By Abu Dzarr
When starting a discussion, it is important to begin with a good definition. In her presentation she started her definition emphasizing on immune mechanism. Platelet destruction in ITP are achieved via various mechanisms. Hence a generic beginning would be a better approach. This definition I borrowed from e-medicine. Immune thrombocytopeni c purpura (ITP) is a clinical syndrome in which a decreased number of circulating platelets (thrombocytopen i a) manifests as a bleeding tendency. I may slightly modify this into like this. 'ITP is a clinical syndrome in which immune mediated mechanism resulted in decreased number of circulating platelets manifesting as a bleeding tendency' :-)
29.06.10 07:28
By Abu Dzarr
Ujian buat kali kedua
29.06.10 06:52
By Kakak Tua
testing
29.06.10 06:45
By Kakak Tua